john hawks weblog

paleoanthropology, genetics and evolution

Pääbo on Neandertal sequencing

Mon, 2009-07-13 20:55 -- John Hawks

On Edge, Svante Pääbo has a long and interesting narrative about Neandertal genetics, FoxP2 mice, his own biography, and everything else. Nothing new to be had, but much interesting background about old stuff.

How can I resist quoting this passage?

Probably the most likely thing was that this was introduced at 454 at the same time they were sequencing Jim Watson — I wouldn't be totally surprised if we tried to investigate this and there was some slight mixture of Jim Watson with the Neanderthal sequence there.

Poor Watson -- his DNA has been everywhere!

And why paleoanthropologists have such big arguments:

As an outsider to paleontologists, I'm often rather surprised about how much scientists fight in paleontology. And I am thinking about why that is the case. Why do we have less vicious fights in molecular biology, for example? I suppose the reason is that paleontology is a rather data-poor science. There are probably more paleontologists than there are important fossils in the world. To make a name for yourself is to find a new interpretation for those fossils that are extant. This always goes against some earlier person's interpretation, who will not like it very much.

Yes, I'm sure it's true. But you have to admit we have better taste in wine.

Neandertals

For years, I've worked on their bones. Now I'm working on their genes. Read more about the science studying these ancient people.

Denisova

From a finger bone of an ancient human came the record of a completely unexpected population. My lab is working on the science of the Denisova genome.

Acceleration

The advent of agriculture caused natural selection to speed up greatly in humans. We're uncovering some of the ways that populations have rapidly changed during the last 10,000 years.

Malapa

Just outside Johannesburg, the Malapa site is producing some of the most exciting finds in human evolution. This site is the headquarters of the Malapa Soft Tissue Project.