114-year-olds are not mutants!09 Jan 2012
Alexis Madrigal for the Atlantic: “The Surprisingly Mundane Genetic ‘Secrets’ of Earth’s Oldest People”.
Recently, the genomes of two 114-year-olds were published by a Boston University team in Frontiers in Genetics of Aging. Though one older person is believed to have had her genome sequenced, the new duo are the oldest people to have had their genomes published.
Of course, sequencing two genomes to discover no Mendelian variants of large effect on longevity seems like overkill. It’s amazing how much human genetics is driven by an X-Men model of inheritance. Come on, people – learn some evolutionary theory!